Glucose and Cancer

This lecture from the Memorial Sloan-Kettering Cancer Center is over two years old, but the information contained is still relatively unknown. The video is basically a cancer 101 segment in the beginning which progresses into cancer proliferation metabolism; mainly the important role that glucose plays:

Screen Shot 2013-03-09 at 10.23.33 PM

 

Cancer cells seem to seek a high amount of glucose. So one of the cancer therapies they’ve researched is blocking the cancer’s ability to take up glucose with a drug. In the still above, you can see two cancerous hot spots on the liver (T) that disappear post therapy of the glucose blocking drug. Naturally, this will drive increased interest in the development of pharmaceutical treatments…but what about the other obvious issue here? Oh, they address that as well:

Screen Shot 2013-03-09 at 9.18.16 PM

 

The answer is carbohydrates since we’re talking so much about glucose metabolism. The lecturer even points out that fat is not cancerous. So if carbohydrates can be cancerous…and fats aren’t…can diet play a role? Perhaps that is why we can see case studies like this:

Of course case studies are just case studies and we’ll need to wait for some randomized clinical trials to really know how well diet can play a role. If you’re interested in more heavy detailed information about the microbio of cancer you may be interested in watching this lecture: